AICAR 50mg
AMPK-Activating Nucleoside Research Compound | Laboratory Use Only
AICAR is a cell-permeable adenosine analog that is taken up by cells and converted to ZMP, an AMP mimetic that activates AMP-activated protein kinase (AMPK), the cellular energy sensor. It is one of the most widely used pharmacological tools for studying AMPK signaling and cellular energy metabolism in cell-based and preclinical models.
$84.00
Availability: 100 in stock
Product Overview
- Compound: AICAR (5-aminoimidazole-4-carboxamide ribonucleoside, acadesine)
- CAS number: 2627-69-2
- Class: Small-molecule nucleoside (not a peptide)
- Molecular formula and weight: C₉H₁₄N₄O₅, about 258.2 g/mol
- Format: Solid research material; confirm strength and vial size
- Purity: Typically ≥98% (confirm by COA)
- Documentation: Lot-specific Certificate of Analysis (COA)
Research Areas of Interest
- AMPK activation and energy-sensing pathways
- Mitochondrial biogenesis and mitophagy
- Glucose uptake and fatty acid oxidation in cell models
- AMPK/mTOR signaling and cell cycle studies
- Apoptosis and hematologic cell models
- AMPK-independent effects of nucleoside analogs
