Selank
Selank is a synthetic heptapeptide derived from tuftsin, a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) fragment of the immunoglobulin G heavy chain. First described in the late 1990s, Selank extends tuftsin with a Pro-Gly-Pro tripeptide tail, enhancing resistance to enzymatic degradation.
The peptide has a molecular formula of C33H57N11O9, a molecular weight of 751.87 g/mol, and CAS number 129954-34-3. Also referred to as TP-7, Selank is supplied as a white to off-white lyophilized powder that dissolves readily in water. The Pro-Gly-Pro extension protects the peptide from cleavage by prolyl endopeptidases, providing greater stability than native tuftsin.
For research use only. Not approved for human or animal consumption.
Price range: $42.00 through $75.00
Selank is a synthetic heptapeptide composed of seven amino acids with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. First described in the late 1990s, it is structurally derived from tuftsin, a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) fragment of the immunoglobulin G (IgG) heavy chain. The peptide design extends tuftsin with a Pro-Gly-Pro tripeptide tail, similar to the modification used in Semax, to enhance stability and resist enzymatic degradation. The peptide has a molecular formula of C33H57N11O9, a molecular weight of 751.87 g/mol, and CAS number 129954-34-3. Also known as TP-7 or Selanc, it is supplied as a white to off-white lyophilized powder that dissolves readily in water. The Pro-Gly-Pro motif protects against cleavage by prolyl endopeptidases, providing greater solution stability than the parent tuftsin fragment. For research use only. Not approved for human or animal consumption.
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